• In summary current evidence suggests that bone targeted

  2019-05-28

  

  In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in

• Aside from distinct technical approaches used

  2019-05-28

  

  Aside from distinct technical approaches used, the well-established RANKL and RANK expression patterns in the bone further substantiates the expression patterns defined in the current study of OS. RANKL and RANK play major roles in bone metabolism due to the critical role of this pathway in osteocla

• A meta analysis of seven observational studies comparing

  2019-05-28

  

  A meta-analysis of seven observational studies, comparing dabigatran with warfarin, indicated that the ability of dabigatran to prevent ischemic stroke and bleeding outcomes is comparable to that of warfarin, which is consistent with the data obtained from the RE-LY trial [9]. These findings do not

• In our study acute toxicities were mild and there

  2019-05-27

  

  In our study, acute toxicities were mild, and there were no Grade 3 or above hematologic toxicities. Only one patient (3.2%) had Grade 3 esophagus toxicity and three patients (9.7%) had Grade 3 lung toxicity. Compared with studies that investigated regimens of oxaliplatin and 5-FU/leucovorin, the pr

• Letsas et al reported that the prevalence

  2019-05-27

  

  Letsas et al. reported that the prevalence of Brugada-type ECG was 0.34% in men and 0.04% in women in the Greek population [19]. Despite the similar BS gender differences between the Greeks and the Japanese, many multicenter studies performed in Western countries indicated that the frequency of men

• br Materials and methods This study

  2019-05-27

  

  Materials and methods This study included WCD patients with high risk of SCD but did not meet the eligibility criteria for immediate back off of an implantable cardioverter defibrillator (ICD). Current guidelines endorse indications for WCD therapy [5]. Patients with low left ventricular ejection

• br Genetic basis for atrial standstill br Genetic

  2019-05-27

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

• progesterone receptor br Material and methods br Results A

  2019-05-27

  

  Material and methods Results A total of 4014 subjects were enrolled and registered during the initial recruitment progesterone receptor from September 2013 through March 2015. In total, 167 subjects were excluded because of missing pivotal data such as height, body weight, or age (date of bir

• Un peculiar texto de Borges enumera al interior

  2019-05-27

  

  Un peculiar texto de Borges enumera, al interior de su relato, interesantes ejemplos de varias categorías pertenecientes al idioma propuesto por John Wil-kins —un sabio inglés del siglo — cuyo objetivo fue diseñar un lenguaje mucho más completo, abarcador e incluso preciso, en sus descripciones del

• Qu dicen las fechas en que

  2019-05-27

  

  ¿Qué dicen las fechas en que se ha flexibilizado la posición de ambas partes? Veamos una cita elocuente sobre la situación internacional en la década de los años setenta del siglo pasado, marco en el que se mejoraron las relaciones entre Washington y La Habana, bajo el gobierno de James Carter. Por

• Di logo de amigos escritura y ficci n se

  2019-05-27

  

  Diálogo de amigos, escritura y ficción se cruzan desde las primeras páginas: “Por dispares que fuéramos como escritores, la amistad cabía, porque sentíamos una compartida pasión por los libros. Tardes y noches conversamos de Johnson, de De Quincey, de Stevenson, de literatura fantástica, de argument

• br For more than a decade WHO has focused its

  2019-05-27

  

  For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor

• As long as developing world

  2019-05-27

  

  As long as developing-world health systems are ill prepared to offer safe anaesthesia and intensive care to patients in need of surgery, surgically treatable conditions will remain leading causes of death, the world will lose trillions of dollars in gross domestic product, and we in the global healt

• Friberg et al have indicated that the CHA DS

  2019-05-27

  

  Friberg et al. [17] have indicated that the CHA2DS2-VASc score is superior to the CHADS2 score in terms of stroke risk stratification, and the risk of stroke is extremely low among patients with a CHA2DS2-VASc score of in whom antithrombotic therapy is not beneficial and may even increase the risk o

• In addition to being a key

  2019-05-24

  

  In addition to being a key determinant of the risk of acquiring infection, nutritional status is a principal determinant of the health trajectory and outcomes following discharge from hospital. Among Gambian children admitted with pneumonia, even being moderately underweight was associated with a ra

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