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Our results indicate that C CoA is formed in the
2020-06-19
Our results indicate that C75-CoA is formed in the hypothalamus following stereotaxic injection of C75. Inhibition of hypothalamic CPT1 by C75-CoA in vivo, as seen in our experiments, is independent of the putative inhibition by malonyl-CoA, which may be formed after the action of C75 either on FAS
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RQ What are the different factors that influence the decisio
2020-06-19
RQ2: What are the different factors that influence the decision to choose among different component origins? In total eleven factors grouped into three high-level themes that influence the decision to choose a component origin were identified. The project metrics factors are: time, cost, effort and
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The interest for lanthanide and actinide complexes appeared
2020-06-19
The interest for lanthanide and actinide complexes appeared again recently, due to their unique features in the design of Single Molecule Magnets (SMM). Lanthanide SMMs are interesting due to large their intrinsic magnetic anisotropy, but their core 4f orbitals minimally participate in exchange inte
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AZ 10606120 dihydrochloride VHb expression in recombinant E
2020-06-19
VHb expression in recombinant E. coli expressing P4H improved Hyp production, presumably by enhancing oxygen transfer. VHb expression contributed to improving growth and extending the period of exponential growth in both shaker flask culture and bioreactor fermentation. A similar phenomenon was also
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The four other mutations S
2020-06-19
The four other mutations (S281T, V317I, T328A and A329S) were not detected in the absence of the A286S. This could suggest that when all of them are present, there would be a tri-dimensional structural modification that would interfere with the binding of the insecticide and produce different levels
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Social memory is encoded within certain sites but meaning
2020-06-19
Social memory is encoded within certain sites, but meaning depends upon an interpretant (such as a tourist) being able to decode the signs. Memorials, such as cemeteries, require some kind of activity by its visitors for their meanings to be activated (Hutchinson, 2009, Winter, 2010). Following Eden
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Considering these reports and with the aim
2020-06-19
Considering these reports, and with the aim of further investigating the mechanism by which the cAMP-Epac/PKA pathway activates eNOS, we have performed imaging experiments evaluating the effect of drugs that increase cAMP or modify its signalling pathways (PKA or Epac activators and inhibitors) on b
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br Materials and methods br
2020-06-18
Materials and methods Results and discussion Conclusions Acknowledgments This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korean government (MEST) (No. 2011-0030635) and the MarineBio Research Program (NRF-C1ABA001-2011-0018561). The Fonta
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In normal cells the apoptotic stimuli lower the expression
2020-06-18
In normal cells, the apoptotic stimuli lower the expression level of antiapoptotic proteins by increasing turnover rate and preventing the constant degradation of proapoptotic proteins. Thus, the dysregulation of anti-/pro-apoptotic proteins will confer the survival of cancer Oligomycin A via enhanc
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Interaction between neutrophils and ECs
2020-06-18
Interaction between neutrophils and ECs represents the first step of the cellular phase of the inflammatory response, and provide the best condition for the transfer of the PMNL-derived LTA4 to the ECs, leading to the transcellular formation of cysteinyl-LTs. It is intriguing therefore to think that
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System Analysis and Modeling In this work a three level
2020-06-18
System Analysis and Modeling - In this work, a three-level hierarchical modeling – composed by combinatorial and state-space models – is used: (1) First, failure rates () of TMS servers subsystem units are estimated through continuous Markov chains; (2) Then, the single server 3,4-DAA failure rate
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Due to its several industrial applications the recombinant
2020-06-18
Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian PF 04418948 (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et al., 200
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po1 Cardiogenesis is enhanced with timely applicati http www
2020-06-18
Cardiogenesis is enhanced with timely application of Wnt pathway activators and inhibitors. A combination of Wnt/β-catenin signaling pathway activators such as CHIR99021 and inhibitors such as IWP-2 and IWR-1 have been found to be highly efficient cardiomyocyte differentiation protocols [27], [28].
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This review aims to examine
2020-06-18
This review aims to examine the literature on chloride Butaprost in the context of transplacental transport. After a short overview of the general cellular functions of Cl− channels in epithelia and the molecular classifications of these channels, it will focus on the evidence for the presence of c
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br Conclusions br Statement of authorship br Nonaneurysmal s
2020-06-18
Conclusions Statement of authorship Nonaneurysmal subarachnoid hemorrhage (NA-SAH) differs from aneurysmal subarachnoid hemorrhage (SAH) in both clinical course and outcome. In spite of many reports and case series since the first description in 1985, the etiology of NA-SAH remains uncertain
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