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Introduction Myelodysplastic Syndrome MDS is a heterogeneous
2019-04-16
Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal
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br Discussion Chronic myelogenous leukemia CML is a clonal
2019-04-16
Discussion Chronic myelogenous leukemia (CML) is a clonal disorder involving the pluripotent stem cell and is consistently associated with the BCR-ABL1 fusion gene located on the Philadelphia chromosome [1]. The disease typically evolves in 3 distinct clinical stages: chronic and accelerated phas
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mCAP The recently published global consensus recommendations
2019-04-16
The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q
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br Algorithm of treatment approach
2019-04-16
Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar
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Introduction Cardiac resynchronization therapy CRT reduces m
2019-04-16
Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio
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In silico prediction software SIFT PolyPhen CADD
2019-04-16
In silico prediction software, SIFT [51], PolyPhen2 [52], CADD [53], and other prediction systems are useful to evaluate a specific mutation which is detected in a patient. However, even if the in silico software predicts a mutation as pathogenic, we need to examine whether the genetic result is com
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La descripci n arquitect nica de
2019-04-16
La descripción arquitectónica de la quinta es heterogénea, extensa, precisa, sugerente, sin duda uno de los pasajes en El fistol del diablo más revisados y pulidos por Payno, con la totalidad de la novela en mente, por lo tanto pleno de simbolismo histórico-cultural y de presagios. Por principio, el
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To assess quality independent from quantity Imamura and
2019-04-16
To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i
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Desde la perspectiva expuesta la etnicidad
2019-04-16
Desde la perspectiva expuesta, la etnicidad constituye una dimensión potencial de la identidad, fundamentada en un conjunto de elementos que, al seguir la tradición weberiana, pueden abarcar la percepción de origen, cultura, idioma o rasgos fenotípicos compartidos por un conjunto de personas. La adq
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En Por qu construir un
2019-04-15
En “\"Por qué construir un pueblo es la tarea de la política radical?”, Laclau profundiza una tensión en su teoría en el marco de la respuesta (-)-p-Bromotetramisole Oxalate Slavoj zžek. Por un lado, la formalidad de la lógica populista, en principio, impide predicar sus alcances en cuanto a la demo
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br We recently reported associations between
2019-04-15
We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( Antimicrobial resistance is recognised as a serious global he
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br Role of p MAPK signaling in
2019-04-15
Role of p38 MAPK signaling in mutated state or compromised function of p53 The tumor suppressor gene p53 functions as a central node in cellular mechanisms preserving genomic integrity in response to both genotoxic and non-genotoxic stress either by inducing apoptosis or by arresting get married
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br Acknowledgments This study was supported by a grant from
2019-04-15
Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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However during pacing at the most proximal CS electrodes CS
2019-04-15
However, during pacing at the most proximal CS electrodes (CS 9–10), although the conduction time to the CS 1–2 was prolonged, the septal to lateral activation sequence (CS 5–6 to CS 3–4 to CS 1–2) indicated the presence of residual conduction on the MI line (Fig. 3B). Detailed mapping on the MI lin
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br Case report A years old
2019-04-15
Case report A 51-years-old man visited our hospital presenting with a palpable mass over the right inguinal area which had persisted for 3 months. This lesion was approximately 3–4 cm, firm and had progressively enlarged. Laboratory data showed no remarkable anomaly except elevated lactate dehydr
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