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Introduction Cancer therapy has evolved throughout the decad
2019-05-09
Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of
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In the current era nearly all cases
2019-05-09
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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br Introduction Since Reekers and Bolia introduced
2019-05-08
Introduction Since Reekers and Bolia introduced subintimal angioplasty, the trans-subintimal route has become the preferred technique to advance the guidewire through a totally occluded and often heavily calcified lesion, especially in the aortoiliac segment. The technical failure was seen in 20–
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myosin inhibitor br Case report At that
2019-05-08
Case report At that time, her laboratory examinations showed hemoglobin (Hb) of 10.4 g/dl (normal: 11.3–15.3), and platelets of 36,000/mm3 (normal: 150,000–400,000), and WBC count of 3800/mm3 (normal: 4000–11,000). The liver function showed serum albumin was 3.2 g/dl, total bilirubin was 1.7 mg/d
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Introduction Osteosarcoma OS is the
2019-05-08
Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple ther
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ret pathway br Conflict of interest br
2019-05-08
Conflict of interest Acknowledgments This study was supported by the National Natural Science Foundation of China (Nos. 81273501 and 81470378). Introduction Sudden cardiac death (SCD) is a tragic event and the aftermath is devastating to the surviving family and community. SCD occurs in ne
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Polysaccharides fatty acid esters glycosides iridoids anthra
2019-05-08
Polysaccharides, fatty rilpivirine esters, glycosides, iridoids, anthraquinones, flavonoids, phytosterols, carotenoids, vitamin A, antraquinones, potassium, and others have been identified as putative active ingredients in NJ. Our previous report indicated that gentisic, p-hydroxybenoic, and chlorog
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Numbers studies also showed that the MSCs have
2019-05-08
Numbers studies also showed that the MSCs have the capacity to differentiate into multiple mesenchymal tissues both in vitro and in vivo, including osteoblast [25,34], condrocyte [35,36], adipocyte [37,38], tendon [39,40], skeletal muscle cells [39], cardiomyocyte [41,42] and hematopoietic supportin
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Combined use of two AADs was more frequent in persistent
2019-05-08
Combined use of two AADs was more frequent in persistent (6.7%) and LS-persistent AF (7.5%) patients than in PAF patients (2.8%, pdna-pk inhibitor prescribed at the time of discharge in the three AF types. The choice of bepridil was dependent on the type of AF (PAF 10.6% vs. non-PAF 30.3%, p Discu
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In this case report we
2019-05-08
In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation
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Dexamethasone with its anti inflammatory properties has been
2019-05-08
Dexamethasone, with its anti-inflammatory properties, has been shown to be an effective medication in the treatment of pain flare and is hypothesized to prevent the phenomenon as well [12]. Despite a lack of literature investigating this hypothesis, currently published phase I and II trials have pro
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A first step forward would be to establish a public
2019-05-07
A first step forward would be to establish a public-health-oriented commission or agency charged specifically with developing controls over the alcohol market and a strategy for reducing levels of alcohol consumption and problems, drawing on the strategies agreed on in the WHO Global Strategy for Re
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death associated protein kinase H consenso na literatura de
2019-05-07
Há consenso na literatura de que as cebs criaram espaços (em meio à repressão), para death associated protein kinase organização dos interesses coletivos das comunidades. No entanto, Reginaldo Prandi considera superestimada a participação política promovida pelas cebs, e identifica algum grau de cen
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To the best of our knowledge
2019-05-07
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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purchase LY 2109761 br Methods br Results br Discussion A ba
2019-05-07
Methods Results Discussion A. baumannii remains one of the most common nosocomial pathogens and frequent causes of outbreaks in burn wound infections. Unfortunately, most of the isolates are resistant to antimicrobial agents. β-Lactamases are microbial enzymes that hydrolytically inactivate
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